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Oxytocin research is foundational to women’s reproductive physiology and is heavily referenced in studies of childbirth, lactation, mood and post-partum biology.
Endogenous oxytocin drives uterine contraction during labor and milk ejection during breastfeeding. Clinical and pre-clinical research in female cohorts continues to characterize receptor density, pulsatility and dose-response across the peripartum period.
Research has examined oxytocin signaling in maternal-infant bonding and in mood-related endpoints during the post-partum period. Sex-based differences in oxytocin receptor expression are documented across hypothalamic and limbic regions.
Intranasal oxytocin research has measured social cognition, trust and stress-reactivity endpoints in mixed-sex cohorts, with sub-analyses exploring interactions with cyclic estrogen and progesterone.
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